Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521814 | 0.83 | CYP3A4 (0.44) | CYP3A4HPGDALDH1A1POLBKDM4E | |
| SCHEMBL24915777 | 0.83 | MAPT (0.42) | HPGDALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL20680327 | 0.78 | LMNA (0.38) | CYP3A4HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29923651 | 0.75 | L3MBTL1 (0.41) | HPGDALDH1A1POLBKDM4EPRNP | |
| SCHEMBL9830239 | 0.75 | NQO2 (0.46) | HPGDALDH1A1POLBCRHR1PRNP | |
| SCHEMBL29923598 | 0.74 | HPGD (0.48) | CYP3A4HPGDALDH1A1POLBKDM4E | |
| SCHEMBL22750299 | 0.73 | CRHR1 (0.47) | CYP3A4ALDH1A1POLBCRHR1PRNP | |
| SCHEMBL29923906 | 0.73 | CRHR1 (0.47) | CYP3A4ALDH1A1POLBCRHR1PRNP | |
| SCHEMBL24916103 | 0.73 | NOS3 (0.41) | CYP3A4HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL29924149 | 0.73 | NOS3 (0.41) | CYP3A4HPGDALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |