SCHEMBL29923962

SCHEMBL29923962

O=C1CCc2cc(-c3ccc(Cl)c(Cl)c3)ccc2N1CCN1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 3/20 0.48
NOS1 P29475 3/20 0.48
ADRA1B P35368 2/20 0.47
NOS2 P35228 1/20 0.46
HTR1A P08908 1/20 0.46
DRD2 P14416 5/20 0.45
DRD4 P21917 5/20 0.45
DRD3 P35462 5/20 0.45
HRH3 Q9Y5N1 3/20 0.42
KCNH2 Q12809 1/20 0.42
SIGMAR1 Q99720 3/20 0.42
CYP1A2 P05177 2/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901282 1.00 NOS3 (0.48) NOS3NOS1ADRA1BNOS2HTR1A
SCHEMBL28901351 0.91 ADRA1B (0.47) NOS3NOS1ADRA1BHTR1ADRD2
SCHEMBL29924398 0.91 ADRA1B (0.47) NOS3NOS1ADRA1BHTR1ADRD2
SCHEMBL28901360 0.80 SIGMAR1 (0.47) ADRA1BHTR1ADRD2DRD4DRD3
SCHEMBL29924454 0.80 SIGMAR1 (0.47) ADRA1BHTR1ADRD2DRD4DRD3
SCHEMBL2675486 0.79 ATAD2 (0.62) NOS3NOS1ADRA1BNOS2DRD2
SCHEMBL2676164 0.77 ATAD2 (0.63) NOS3NOS1ADRA1BNOS2DRD2
SCHEMBL3301768 0.77 CYP1A2 (0.44) DRD2DRD4DRD3CYP1A2CYP11B1
SCHEMBL29923967 0.76 CHRM1 (0.53) NOS3NOS1NOS2DRD2DRD4
SCHEMBL28901304 0.76 CHRM1 (0.53) NOS3NOS1NOS2DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN claimed
CN-115073370-B Novel alkylaminos or salts, isomers, preparation method and application thereof 成都硕德药业有限公司 2024-12-17 CN disclosed
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN disclosed