Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.67 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.67 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112478 | 1.00 | LMNA (0.81) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL29837028 | 1.00 | LMNA (0.81) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL29748937 | 1.00 | LMNA (0.81) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL14691397 | 0.99 | LMNA (0.79) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL30816021 | 0.89 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL6130845 | 0.89 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL29822950 | 0.89 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL466528 | 0.89 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL466529 | 0.89 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL8199189 | 0.88 | DRD2 (0.71) | LMNAKDM4EALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073373-A | Method for asymmetric synthesis of (R) -5' -methoxy labdanin | 广东嘉博制药有限公司 | 2022-09-20 | — | — | CN | disclosed |