SCHEMBL29924546

SCHEMBL29924546

CCCCOC(=O)N1CCCC1c1ccc(C=O)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 6/20 0.39
SIGMAR1 Q99720 6/20 0.39
RIPK1 Q13546 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
GCK P35557 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
SCD O00767 2/20 0.35
SCD5 Q86SK9 1/20 0.35
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
ACE P12821 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619441 0.82 RIPK1 (0.46) RIPK1L3MBTL1MEN1KMT2A
SCHEMBL31421713 0.78 LMNA (0.47) TMEM97SIGMAR1RIPK1L3MBTL1SMN1; SMN2
SCHEMBL932669 0.77 RIPK1 (0.46) RIPK1GCK
SCHEMBL12478146 0.75 TMEM97 (0.49) TMEM97SIGMAR1RIPK1L3MBTL1SMN1; SMN2
SCHEMBL24619724 0.75 GAA (0.43) TMEM97SIGMAR1RIPK1SMN1; SMN2GAA
SCHEMBL29540420 0.74 TMEM97 (0.56) TMEM97SIGMAR1RIPK1L3MBTL1CHRM2
SCHEMBL22721972 0.74 TMEM97 (0.56) TMEM97SIGMAR1RIPK1L3MBTL1CHRM2
SCHEMBL31421732 0.74 ALDH1A1 (0.44) TMEM97SIGMAR1SMN1; SMN2MEN1KMT2A
SCHEMBL3378097 0.74 TMEM97 (0.51) TMEM97SIGMAR1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL24619436 0.72 RIPK1 (0.46) RIPK1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 EP disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 WO disclosed