Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947353 | 1.00 | KMT2A (0.31) | KMT2ABACE1 | |
| SCHEMBL30404309 | 1.00 | KMT2A (0.31) | KMT2ABACE1 | |
| SCHEMBL31009242 | 0.79 | PDE2A (0.36) | BACE1 | |
| SCHEMBL31009251 | 0.79 | TRPV4 (0.36) | KMT2A | |
| SCHEMBL30938761 | 0.78 | CYP11B2 (0.38) | — | |
| SCHEMBL29993382 | 0.75 | PDK2 (0.31) | — | |
| SCHEMBL30680744 | 0.74 | SLC6A4 (0.33) | BACE1 | |
| SCHEMBL30217567 | 0.73 | MAPK1 (0.34) | KMT2A | |
| SCHEMBL29800290 | 0.72 | CXCR3 (0.37) | KMT2A | |
| SCHEMBL14625577 | 0.71 | PTGDR (0.37) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-113853371-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-4334304-A1 | BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| CN-117279904-A | GLP-1 receptor agonists, pharmaceutical compositions comprising same and methods of making same | 株式会社LG化学 | 2023-12-22 | — | — | CN | disclosed |
| CN-117222644-A | 2- ((4- ((S) -2- (4-chloro-2-fluorophenyl) -2-methylbenzo [ d ] [1,3] dioxol-4-yl) piperidin-1-yl) methyl) -1- (((S) -oxetan-2-yl) methyl) -1H-imidazole derivatives as GLP1 receptor activators for the treatment of obesity | 诺华股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116547278-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116323599-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116217558-A | GLP-1 receptor agonist, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115667250-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115521297-A | 5,6-dihydro-1,2,4-triazines and their pharmaceutical use as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2022-12-27 | — | — | CN | disclosed |
| CN-115335374-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-11-11 | — | — | CN | disclosed |
| WO-2022235717-A1 | BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |