Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149855 | 0.86 | DAPK3 (0.36) | PTGER4KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL29924912 | 0.86 | HSD17B10 (0.44) | HSD17B10TSHRGAAPTGER4KDM4E | |
| SCHEMBL29924211 | 0.81 | MAPT (0.36) | HSD17B10TSHRGAAKDM4EALDH1A1 | |
| SCHEMBL6774504 | 0.78 | HSD17B10 (0.42) | HSD17B10TSHRGAAKDM4EALDH1A1 | |
| SCHEMBL29924614 | 0.76 | CSNK2A2 (0.42) | HSD17B10TSHRGAAPTGER4KDM4E | |
| SCHEMBL27286488 | 0.74 | HSD17B10 (0.43) | HSD17B10TSHRGAAKDM4EALDH1A1 | |
| SCHEMBL29149723 | 0.72 | DAPK3 (0.41) | PTGER4KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL24401142 | 0.71 | ALDH1A1 (0.36) | HSD17B10TSHRGAAKDM4EALDH1A1 | |
| SCHEMBL24401144 | 0.70 | MAPT (0.36) | HSD17B10TSHRGAAKDM4EALDH1A1 | |
| SCHEMBL24574867 | 0.70 | ALDH1A1 (0.34) | HSD17B10TSHRGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |