SCHEMBL29926409

SCHEMBL29926409

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nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 2/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ SDCBP O00560 3/20 0.37
▸ SDC2 P34741 3/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ MME P08473 1/20 0.37
▸ EPHX2 P34913 1/20 0.36
▸ CTSD P07339 1/20 0.35
▸ PLA2G2A P14555 1/20 0.35
▸ PLA2G5 P39877 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ MBTPS1 Q14703 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15756817 0.94 NPSR1 (0.43) NPSR1SMN1; SMN2SDCBPSDC2ALDH1A1
SCHEMBL15756824 0.94 NPSR1 (0.43) NPSR1SMN1; SMN2SDCBPSDC2ALDH1A1
SCHEMBL29967328 0.92 NPSR1 (0.42) NPSR1SMN1; SMN2SDCBPSDC2ALDH1A1
SCHEMBL29612414 0.91 NPSR1 (0.36) NPSR1SMN1; SMN2SDCBPSDC2ALDH1A1
SCHEMBL30064543 0.89 CTSB (0.46) CTSD
SCHEMBL24191292 0.89 MME (0.37) MMECTSD
SCHEMBL29380611 0.89 NPSR1 (0.47) NPSR1SMN1; SMN2SDCBPSDC2ALDH1A1
SCHEMBL38665440 0.85 QRFPR (0.37) —
SCHEMBL29980033 0.84 LMNA (0.43) ALDH1A1MMEPOLB
SCHEMBL29387536 0.84 MME (0.43) MMECTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 — — US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 — — US disclosed
US-12043659-B2 Humanized and de-immunized antibodies VIVORYON THERAPEUTICS N.V. (DE) 2024-07-23 — — US disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 NPSR1 2800/4885SMN1; SMN2 3039/4885SDCBP 3177/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 NPSR1 3781/4885SMN1; SMN2 4094/4885SDCBP 4364/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT NPSR1 3358/4885SMN1; SMN2 4669/4885SDCBP 4787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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