Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496935 | 0.78 | CA1 (0.32) | — | |
| SCHEMBL3631455 | 0.71 | KDM4E (0.37) | KDM4E | |
| SCHEMBL946454 | 0.71 | KDM4E (0.37) | KDM4E | |
| SCHEMBL6333240 | 0.71 | KDM4E (0.37) | KDM4E | |
| SCHEMBL7373065 | 0.71 | LMNA (0.39) | KDM4E | |
| Piperazine SCHEMBL28325908 | 0.67 | — | — | |
| SCHEMBL5734016 | 0.67 | KDM4E (0.46) | KDM4EF13A1TGM2TGM1 | |
| SCHEMBL6308620 | 0.67 | CA1 (0.34) | KDM4E | |
| Hydrochloric Acid SCHEMBL998901 | 0.67 | GNAI3 (0.43) | KDM4E | |
| SCHEMBL2921111 | 0.65 | KDM4E (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209990-B | Combretastatin derivative and antibody drug conjugate thereof | 上海科技大学 | 2022-10-14 | — | — | CN | disclosed |