Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065 | 0.87 | MDM2 (0.68) | MDM2KMT2ACES2LMNACES1 | |
| SCHEMBL10988389 | 0.83 | MDM2 (0.53) | MDM2MMEPDPK1MEN1KMT2A | |
| SCHEMBL31561617 | 0.81 | KMT2A (0.57) | MDM2MMEGPR52PDPK1NPC1 | |
| SCHEMBL18248079 | 0.80 | KDM6B (0.56) | MMENPC1RAB9AMEN1KMT2A | |
| SCHEMBL1768284 | 0.80 | KDM6B (0.56) | MMENPC1RAB9AMEN1KMT2A | |
| SCHEMBL1768283 | 0.80 | KDM6B (0.56) | MMENPC1RAB9AMEN1KMT2A | |
| SCHEMBL10830533 | 0.79 | ALDH1A1 (0.56) | MDM2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10829586 | 0.79 | LDHA (0.58) | MDM2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19088471 | 0.76 | LTA4H (0.50) | MMENPC1RAB9AMEN1KMT2A | |
| SCHEMBL18256456 | 0.76 | LTA4H (0.50) | MMENPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675715-B | Difuranopyridine derivative and preparation method thereof | 江苏建筑职业技术学院 | 2022-10-18 | — | — | CN | disclosed |