Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23075395 | 1.00 | TBXAS1 (0.43) | TBXAS1NAMPTCYP3A4GPR119RIPK1 | |
| SCHEMBL20029212 | 0.87 | SCD (0.47) | RIPK1SCD | |
| SCHEMBL23075458 | 0.85 | CYP17A1 (0.49) | NAMPTGPR119RIPK1GRM1SCD | |
| SCHEMBL28714232 | 0.81 | KDM1A (0.43) | GPR119SCD | |
| SCHEMBL29467161 | 0.81 | KDM1A (0.43) | GPR119SCD | |
| SCHEMBL23068606 | 0.81 | TBXAS1 (0.52) | TBXAS1NAPRT | |
| SCHEMBL23075460 | 0.80 | RIPK1 (0.43) | NAMPTGPR119RIPK1GRM5GRM1 | |
| SCHEMBL28719227 | 0.80 | SCD (0.43) | SCD | |
| SCHEMBL28707994 | 0.80 | GPR119 (0.42) | GPR119RIPK1GRM5GRM1SCD | |
| SCHEMBL29467175 | 0.80 | GPR119 (0.42) | GPR119RIPK1GRM5GRM1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761398-B | Heterocyclic RIP1 kinase inhibitors | 里格尔药品股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-117083270-A | Heterocyclic RIP1 kinase inhibitors | 里格尔药品股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114761398-A | Heterocyclic RIP1 kinase inhibitors | 里格尔药品股份有限公司 | 2022-07-15 | — | — | CN | disclosed |