Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929666 | 0.78 | TLR7 (0.55) | KMT2AALDH1A1RAB9ABACE1 | |
| SCHEMBL12014862 | 0.69 | MEN1 (0.55) | MEN1KMT2AATMKDRHSD17B10 | |
| SCHEMBL3340310 | 0.69 | DCPS (0.63) | KMT2AHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL29663295 | 0.69 | DCPS (0.63) | KMT2AHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL8942018 | 0.69 | TSHR (0.58) | MEN1KMT2AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL29927588 | 0.69 | AXL (0.51) | AXLATMALDH1A1HRH4SMN1; SMN2 | |
| SCHEMBL13992609 | 0.68 | MEN1 (0.94) | MEN1KMT2AATMHSD17B10ALDH1A1 | |
| SCHEMBL6181854 | 0.67 | HTT (0.47) | KMT2AALDH1A1NUDT1KDM4ELMNA | |
| SCHEMBL31663100 | 0.67 | KMT2A (0.97) | MEN1KMT2AATMHSD17B10ALDH1A1 | |
| SCHEMBL28855851 | 0.65 | LMNA (0.52) | MEN1KMT2AATMKDRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |