Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 5/20 | 0.40 |
| ▸ | JAK3 | P52333 | 4/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902711 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BJAK1JAK2JAK3 | |
| SCHEMBL24150592 | 0.84 | MTNR1A (0.38) | MTNR1AMTNR1BJAK1JAK2JAK3 | |
| SCHEMBL24150591 | 0.83 | KMO (0.50) | JAK2MAPT | |
| SCHEMBL3712173 | 0.82 | LMNA (0.49) | MTNR1AMTNR1BJAK1JAK2JAK3 | |
| SCHEMBL15819715 | 0.76 | JAK1 (0.58) | JAK1JAK2JAK3TYK2MAPT | |
| SCHEMBL28139552 | 0.76 | STK17B (0.52) | MTNR1AMTNR1BABL1 | |
| SCHEMBL30380172 | 0.76 | STAT6 (0.41) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL14485047 | 0.75 | KMT2A (0.45) | JAK1JAK2JAK3 | |
| Methylene Chloride SCHEMBL28101723 | 0.74 | STK17B (0.50) | MTNR1AMTNR1BABL1 | |
| SCHEMBL28793690 | 0.74 | RPS6KA3 (0.33) | RPS6KA3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |