Hypolaetin

Hypolaetin

SCHEMBL29929136

O=c1cc(-c2ccc(O)c(O)c2)oc2c(O)c(O)cc(O)c12

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.69
TERT O14746 1/20 0.67
BRD4 O60885 1/20 0.67
AKT1 P31749 1/20 0.62
KDM4E B2RXH2 3/20 0.61
MEN1 O00255 3/20 0.61
MAPT P10636 3/20 0.61
ALOX15 P16050 3/20 0.61
KMT2A Q03164 3/20 0.61
POLH Q9Y253 3/20 0.61
SLCO2B1 O94956 2/20 0.61
ALDH1A1 P00352 2/20 0.61
GLA P06280 2/20 0.61
CYP19A1 P11511 2/20 0.61
HPGD P15428 2/20 0.61
DAPK1 P53355 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX5 P09917 2/20 0.61
CYP2C9 P11712 2/20 0.61
ALOX12 P18054 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypolaetin SCHEMBL7743466 1.00 BCL2 (0.69) BCL2TERTBRD4AKT1KDM4E
Hypolaetin SCHEMBL29929121 1.00 BCL2 (0.69) BCL2TERTBRD4AKT1KDM4E
Hypolaetin SCHEMBL29435843 1.00 BCL2 (0.69) BCL2TERTBRD4AKT1KDM4E
SCHEMBL31051320 0.87 KDM4E (0.62) BCL2TERTBRD4AKT1KDM4E
SCHEMBL6614337 0.87 KDM4E (0.62) BCL2TERTBRD4AKT1KDM4E
SCHEMBL6801132 0.87 TERT (0.64) BCL2TERTBRD4KDM4EMEN1
SCHEMBL29435853 0.86 CBS (0.78) TERTKDM4EMEN1MAPTALOX15
SCHEMBL28986431 0.86 CBS (0.78) TERTKDM4EMEN1MAPTALOX15
SCHEMBL12470189 0.86 KDM4E (0.72) BCL2TERTBRD4KDM4EMEN1
SCHEMBL476215 0.86 CBS (0.78) TERTKDM4EMEN1MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed