SCHEMBL476215

SCHEMBL476215

O=c1cc(-c2ccc(O)cc2)oc2c(O)c(O)cc(O)c12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CBS P35520 2/20 0.78
▸ CDK5 Q00535 2/20 0.78
▸ CDK5R1 Q15078 2/20 0.78
▸ PTPN1 P18031 2/20 0.78
▸ KMT2A Q03164 4/20 0.72
▸ PKM P14618 4/20 0.72
▸ MAPT P10636 4/20 0.72
▸ KDM4E B2RXH2 3/20 0.72
▸ APEX1 P27695 3/20 0.72
▸ TDP1 Q9NUW8 2/20 0.72
▸ POLB P06746 2/20 0.72
▸ RECQL P46063 2/20 0.72
▸ BLM P54132 2/20 0.72
▸ MCL1 Q07820 2/20 0.72
▸ INPPL1 O15357 1/20 0.72
▸ ALPL P05186 1/20 0.72
▸ ALPI P09923 1/20 0.72
▸ GAA P10253 1/20 0.72
▸ ALPG P10696 1/20 0.72
▸ PFKFB3 Q16875 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435853 1.00 CBS (0.78) CBSCDK5CDK5R1PTPN1KMT2A
SCHEMBL28986431 1.00 CBS (0.78) CBSCDK5CDK5R1PTPN1KMT2A
Cupressuflavone SCHEMBL31670258 0.88 CBS (1.00) CBSCDK5CDK5R1PTPN1KMT2A
Cupressuflavone SCHEMBL505213 0.88 CBS (1.00) CBSCDK5CDK5R1PTPN1KMT2A
Norwogonin SCHEMBL30485998 0.88 GABRP (0.68) CBSCDK5CDK5R1PTPN1KMT2A
SCHEMBL24840880 0.88 KMT2A (0.72) CBSCDK5CDK5R1PTPN1KMT2A
Norwogonin SCHEMBL760431 0.88 GABRP (0.68) CBSCDK5CDK5R1PTPN1KMT2A
Cupressuflavone SCHEMBL4650575 0.86 CBS (0.97) CBSCDK5CDK5R1PTPN1KMT2A
Hypolaetin SCHEMBL29929136 0.86 BCL2 (0.69) CBSCDK5CDK5R1PTPN1KMT2A
Hypolaetin SCHEMBL29435843 0.86 BCL2 (0.69) CBSCDK5CDK5R1PTPN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 — — EP claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 — — WO claimed
US-20250011393-A1 FLAVONOID-COLLAGEN CROSSLINKED ANTIOXIDANT HYDROGEL NORTH CAROLINA STATE UNIVERSITY 2025-01-09 — — US claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 — — WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 — — WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
CN-113046333-B Flavone-8-hydroxylase and application thereof in synthesis of 8-hydroxyflavone compound 中国科学院天津工业生物技术研究所 2023-02-17 — — CN claimed
CN-114166961-B Method for measuring phenolic compounds in citrus juice product and pretreatment method thereof 西南大学 2022-11-22 — — CN claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
CN-113046333-A Flavone-8-hydroxylase and application thereof in synthesis of 8-hydroxyflavone compound 中国科学院天津工业生物技术研究所 2021-06-29 — — CN claimed
WO-2001085183-A2 PREPARATION FOR THE PREVENTION AND TREATMENT OF OCULAR DISORDERS N.V. NUTRICIA (NL) 2001-11-15 — — WO claimed
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 — — EP disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 — — US disclosed
US-5773462-A INFLUENZA THERAPY MEDICHEM RESEARCH, INC. (US) 1998-06-30 — — US disclosed
EP-0833631-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1998-04-08 — — EP disclosed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB CBS 1497/4885CDK5 890/4885CDK5R1 924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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