Hypolaetin

Hypolaetin

SCHEMBL29435843

O=c1cc(-c2ccc(O)c(O)c2)oc2c(O)c(O)cc(O)c12

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 1/20 0.69
▸ TERT O14746 1/20 0.67
▸ BRD4 O60885 1/20 0.67
▸ AKT1 P31749 1/20 0.62
▸ KDM4E B2RXH2 3/20 0.61
▸ MEN1 O00255 3/20 0.61
▸ MAPT P10636 3/20 0.61
▸ ALOX15 P16050 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ POLH Q9Y253 3/20 0.61
▸ SLCO2B1 O94956 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ GLA P06280 2/20 0.61
▸ CYP19A1 P11511 2/20 0.61
▸ HPGD P15428 2/20 0.61
▸ DAPK1 P53355 2/20 0.61
▸ CYP3A4 P08684 2/20 0.61
▸ ALOX5 P09917 2/20 0.61
▸ CYP2C9 P11712 2/20 0.61
▸ ALOX12 P18054 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypolaetin SCHEMBL7743466 1.00 BCL2 (0.69) BCL2TERTBRD4AKT1KDM4E
Hypolaetin SCHEMBL29929121 1.00 BCL2 (0.69) BCL2TERTBRD4AKT1KDM4E
Hypolaetin SCHEMBL29929136 1.00 BCL2 (0.69) BCL2TERTBRD4AKT1KDM4E
SCHEMBL6614337 0.87 KDM4E (0.62) BCL2TERTBRD4AKT1KDM4E
SCHEMBL31051320 0.87 KDM4E (0.62) BCL2TERTBRD4AKT1KDM4E
SCHEMBL6801132 0.87 TERT (0.64) BCL2TERTBRD4KDM4EMEN1
SCHEMBL476215 0.86 CBS (0.78) TERTKDM4EMEN1MAPTALOX15
SCHEMBL28986431 0.86 CBS (0.78) TERTKDM4EMEN1MAPTALOX15
SCHEMBL29435853 0.86 CBS (0.78) TERTKDM4EMEN1MAPTALOX15
SCHEMBL12470189 0.86 KDM4E (0.72) BCL2TERTBRD4KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 — — EP claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 — — WO claimed
US-20250011393-A1 FLAVONOID-COLLAGEN CROSSLINKED ANTIOXIDANT HYDROGEL NORTH CAROLINA STATE UNIVERSITY 2025-01-09 — — US claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 — — WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
US-12569530-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-03-10 — — US disclosed
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 — — EP disclosed
US-12474327-B2 Metabolic profiling for the diagnosis of a subset of idiopathic autism spectrum disorder patients, ADS Phenotype 1 STALICLA SA (CH) 2025-11-18 — — US disclosed
US-12453799-B1 Bioadhesive for medical and dental applications IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-10-28 — — US disclosed
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-08-07 — — US disclosed
US-12318422-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-06-03 — — US disclosed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO disclosed
US-11376570-B1 Method of forming copper oxide-on-copper nanomaterial catalyst mesh KING ABDULAZIZ UNIVERSITY (SA) 2022-07-05 — — US disclosed
US-11364311-B2 Method of identifying ASD phenotype 1 patients Stalicla S.A. (CH) 2022-06-21 — — US disclosed
US-11357871-B2 Challenge test for diagnosing subtypes of ASD Stalicla S.A. (CH) 2022-06-14 — — US disclosed
US-11311492-B1 Carbon nanomedicine with natural ligands KING ABDULAZIZ UNIVERSITY (SA) 2022-04-26 — — US disclosed
US-11234940-B1 Method for making a noble metal nanomedicine KING ABDULAZIZ UNIVERSITY (SA) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB BCL2 646/4885TERT 2536/4885BRD4 2421/4885
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER UGGT1, G6PD, UGT1A3 BCL2 2046/4885TERT 917/4885BRD4 3094/4885
US-12569530-B2 Tannin-based antiproliferative pharmaceutical SLC2A3, SLC2A1, SLC2A8 BCL2 1200/4885TERT 1242/4885BRD4 4153/4885
US-12318422-B2 Tannin-based antiproliferative pharmaceutical UGGT1, G6PD, UGDH BCL2 2020/4885TERT 1621/4885BRD4 3600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback