Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31330735 | 1.00 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL29929108 | 0.88 | NPC1 (0.40) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL1201731 | 0.88 | NPC1 (0.40) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL18869269 | 0.87 | TUBB4A (0.46) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL18487179 | 0.87 | NPC1 (0.37) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL4070144 | 0.84 | KDM4E (0.40) | NPC1RAB9ATUBB4ATUBBTUBA3C | |
| SCHEMBL29929274 | 0.84 | KDM4E (0.40) | NPC1RAB9ATUBB4ATUBBTUBA3C | |
| SCHEMBL3758529 | 0.80 | HCRTR1 (0.35) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL275480 | 0.79 | DRD2 (0.32) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL30177122 | 0.79 | DRD2 (0.32) | PDE4BPDE4APDE4CPDE4DPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574510-B1 | SUSBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-09 | — | — | EP | disclosed |
| CN-1824662-B | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG | 2010-08-04 | — | — | CN | disclosed |
| US-7691785-B2 | Pyridine-3-ketone compound; plant growth controllers | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080274891-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-7378375-B1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| CN-1951918-A | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-04-25 | — | — | CN | disclosed |
| CN-1824662-A | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-30 | — | — | CN | disclosed |
| CN-1231476-C | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-14 | — | — | CN | disclosed |
| EP-1574510-A1 | Substituted pyridine herbicides | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| US-6838564-B2 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040097729-A1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. | 2004-05-20 | — | — | US | disclosed |
| CN-1436184-A | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2003-08-13 | — | — | CN | disclosed |
| EP-1286985-A1 | SUBSTITUTED PYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094339-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274891-A1 | SUBSTITUTED PYRIDINE HERBICIDES | DDT, CYP1A1, CYP1B1 | PDE4B 1624/4885PDE4A 1429/4885PDE4C 1532/4885 |
| US-20040097729-A1 | Substituted pyridine herbicides | DDT, CYP1A1, CYP1B1 | PDE4B 1542/4885PDE4A 1434/4885PDE4C 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.