Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 12/20 | 0.76 |
| ▸ | TLR2 | O60603 | 12/20 | 0.76 |
| ▸ | FBP1 | P09467 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 8/20 | 0.62 |
| ▸ | MAOB | P27338 | 8/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902707 | 1.00 | TLR4 (0.76) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL510207 | 0.86 | TLR4 (1.00) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL510208 | 0.86 | TLR4 (1.00) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL4619916 | 0.80 | TLR4 (0.70) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL4619911 | 0.80 | TLR4 (0.70) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL21657641 | 0.80 | MAOA (0.54) | TLR4TLR2MAOAMAOB | |
| SCHEMBL29928402 | 0.80 | MAOA (0.54) | TLR4TLR2MAOAMAOB | |
| SCHEMBL278627 | 0.78 | FBP1 (1.00) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL31287227 | 0.78 | FBP1 (1.00) | TLR4TLR2FBP1MAOAMAOB | |
| SCHEMBL8765211 | 0.78 | FBP1 (1.00) | TLR4TLR2FBP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |