Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464829 | 0.87 | ALOX5 (0.39) | ALOX5IDO1TDO2TAAR1CHRNB2 | |
| SCHEMBL22995905 | 0.80 | ALOX5 (0.39) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL13848615 | 0.80 | CHRNB2 (0.36) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL9880967 | 0.78 | ALOX5 (0.38) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL14516277 | 0.77 | NR1I2 (0.41) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL941963 | 0.76 | NR1I2 (0.46) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL20963155 | 0.76 | ALOX5 (0.36) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL12462086 | 0.76 | ALOX5 (0.36) | ALOX5IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL9325784 | 0.75 | — | — | |
| SCHEMBL2009597 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184909-A1 | CROSSLINKABLE POLYMERS WITH HETEROAROMATIC GROUPS | HENKEL AG & CO. KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2195353-A1 | CROSSLINKABLE POLYMERS WITH HETEROAROMATIC GROUPS | Henkel AG & Co. KGaA (DE) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009043655-A1 | CROSSLINKABLE POLYMERS WITH HETEROAROMATIC GROUPS | HENKEL AG & CO. KGAA (DE) | 2009-04-09 | — | — | WO | disclosed |