Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.77 |
| ▸ | MIF | P14174 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.66 |
| ▸ | MAOA | P21397 | 4/20 | 0.66 |
| ▸ | MAOB | P27338 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363761 | 0.92 | KDM4E (0.72) | KDM4EMAPTNPC1RAB9APOLB | |
| Calycosin SCHEMBL73013 | 0.87 | KDM4E (1.00) | KDM4EMAPTNPC1RAB9APOLB | |
| Calycosin SCHEMBL30335127 | 0.87 | KDM4E (1.00) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL23028467 | 0.84 | ALDH2 (0.86) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL11561656 | 0.84 | MAPT (0.63) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL29482686 | 0.81 | XDH (1.00) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL29482679 | 0.81 | XDH (1.00) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL73012 | 0.81 | XDH (1.00) | KDM4EMAPTNPC1RAB9APOLB | |
| SCHEMBL29392289 | 0.81 | XDH (1.00) | KDM4EMAPTNPC1RAB9APOLB | |
| Cladrin SCHEMBL738092 | 0.81 | KDM4E (1.00) | KDM4EMAPTNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |