Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592834 | 0.88 | MERTK (0.39) | DGAT1DYRK1ADYRK1BMERTK | |
| SCHEMBL29930809 | 0.87 | DGAT1 (0.37) | DGAT1DYRK1ADYRK1BMERTKMAPT | |
| SCHEMBL29930401 | 0.87 | DYRK1B (0.40) | DGAT1DYRK1BMERTKPDE1B | |
| SCHEMBL29930779 | 0.86 | AXL (0.41) | DGAT1DYRK1ADYRK1BMERTKMAPT | |
| SCHEMBL29930917 | 0.84 | DYRK1B (0.38) | DGAT1DYRK1BMERTK | |
| SCHEMBL29935301 | 0.83 | DGAT1 (0.33) | DGAT1DYRK1B | |
| SCHEMBL29930407 | 0.83 | DYRK1B (0.39) | DGAT1DYRK1BMERTKPDE1B | |
| SCHEMBL29113927 | 0.82 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL29930775 | 0.82 | MAPT (0.35) | DGAT1MAPT | |
| SCHEMBL29930815 | 0.82 | AXL (0.41) | DGAT1DYRK1BMERTKMAPTPDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235097-A1 | PHARMACEUTICAL COMPOSITION CONTAINING NOVEL PYRAZOLO[3,4-B]PYRIDINE DERIVATIVE FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE INCLUDING OBESITY AND DIABETES MELLITUS OR NONALCOHOLIC STEATOHEPATITIS | 한국화학연구원 | 2022-11-10 | — | — | WO | disclosed |