Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 1.00 |
| ▸ | OGFRL1 | Q5TC84 | 14/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lexanopadol SCHEMBL566686 | 1.00 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Lexanopadol SCHEMBL381022 | 1.00 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Lexanopadol SCHEMBL566559 | 1.00 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2829900 | 0.89 | OPRM1 (0.80) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL380515 | 0.87 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL681581 | 0.86 | OPRM1 (0.75) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Cebranopadol SCHEMBL566256 | 0.84 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL16153874 | 0.84 | OPRM1 (0.75) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Cebranopadol SCHEMBL154336 | 0.84 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Cebranopadol SCHEMBL29353179 | 0.84 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11471503-B2 | Use of KOR agonist in combination with MOR agonist in preparing drug for treating pain | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2022-10-18 | — | — | US | claimed |
| CN-111065390-B | Use of a KOR agonist in combination with a MOR agonist for the preparation of a medicament for the treatment of pain | 江苏恒瑞医药股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| US-11471503-B2 | Use of KOR agonist in combination with MOR agonist in preparing drug for treating pain | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2022-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11471503-B2 | Use of KOR agonist in combination with MOR agonist in preparing drug for treating pain | OPRK1, OPRM1, OPRL1 | OPRM1 2/4885OGFRL1 68/4885OPRL1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.