SCHEMBL299309

SCHEMBL299309

C=CCc1c[c]cc(CC=C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.47
GABRB2 P47870 4/20 0.47
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPK1 P28482 1/20 0.38
POLB P06746 2/20 0.36
AKR1B1 P15121 2/20 0.36
GAA P10253 3/20 0.36
XDH P47989 2/20 0.34
KDM4E B2RXH2 2/20 0.34
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ALDH2 P05091 1/20 0.33
HPGD P15428 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3547863 0.81 ALOX5 (0.42) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL3257726 0.81 GABRA1 (0.37) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL6202597 0.81 GABRA1 (0.37) GABRA1GABRB2MAPTPOLBGAA
SCHEMBL7058487 0.78 GABRA1 (0.34) GABRA1GABRB2POLB
SCHEMBL5822189 0.74 GABRA1 (0.50) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL168974 0.73 GABRA1 (0.79) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL4045452 0.73 GABRA1 (0.48) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL4149652 0.73 GABRA1 (0.59) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL15676646 0.72 GABRA1 (0.64) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL1420217 0.71 GABRA1 (0.47) GABRA1GABRB2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110050035-B Solid oleaginous compositions 道达尔销售服务公司 2022-05-13 CN claimed
EP-3081609-B1 BITUMINOUS ADHESIVE BINDER AND USE THEREOF TOTAL MARKETING SERVICES (FR) 2020-06-24 EP claimed
EP-3081609-A1 BITUMINOUS ADHESIVE BINDER AND USE THEREOF TOTAL MARKETING SERVICES (FR) 2016-10-19 EP claimed
EP-1917309-B1 METHOD FOR PREPARING BITUMEN BASE TOTAL MARKETING SERVICES (FR) 2015-11-11 EP claimed
US-7918930-B2 Method for preparing bitumen base TOTAL FRANCE (FR) 2011-04-05 US claimed
US-20080308007-A1 Method for Preparing Bitumen Base TOTAL FRANCE 2008-12-18 US claimed
EP-1917309-A1 METHOD FOR PREPARING BITUMEN BASE Total France (FR) 2008-05-07 EP claimed
WO-2007012665-A1 METHOD FOR PREPARING BITUMEN BASE TOTAL FRANCE (FR) 2007-02-01 WO claimed
US-6949593-B2 Bituminous component, an elastomer and a bisaromatic containing >/= 1 hydroxy group, amide group and/or an ester group KRATON POLYMERS U.S. LLC (US) 2005-09-27 US claimed
EP-1325082-B1 BITUMINOUS COMPOSITION WITH IMPROVED \"WALK-ON-ABILITY\" AND ITS USE IN ROOFING APPLICATIONS KRATON POLYMERS RES BV (NL) 2004-08-04 EP claimed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US claimed
WO-1994022945-A1 METHOD FOR STABILIZING AN ORGANIC MATERIAL WHICH IS SUBJECT TO THERMAL AND/OR OXIDATIVE DETERIORATION AND RESULTING STABILIZED MATERIAL UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-13 WO claimed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US claimed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP claimed
US-4992499-A Using phenolic compound and aromatic amine SHELL OIL COMPANY (US) 1991-02-12 US claimed
EP-0141419-B1 3,5-DIALKYL-4-HYDROXYPHENYL-SUBSTITUTED DERIVATIVES The B.F. GOODRICH Company (US) 1988-03-09 EP claimed
EP-0101042-B1 LIGHT-STABLE POLYOLEFINS BORG-WARNER CHEMICALS INC. (US) 1986-10-29 EP claimed
EP-0101042-A1 Light-stable polyolefins BORG-WARNER CHEMICALS INC. (US) 1984-02-22 EP claimed
US-4410650-A NICKEL COMPLEX OF A PENTAERYTHRITOL PHOSPHITE BORG-WARNER CHEMICALS, INC. (US) 1983-10-18 US claimed
US-4173541-A ANITOXIDANTS CINCINNATI MILACRON CHEMICALS INC. (US) 1979-11-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080308007-A1 Method for Preparing Bitumen Base BET1, AR, CYP11B2 GABRA1 707/4885GABRB2 818/4885MEN1 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.