Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.61 |
| ▸ | GLI1 | P08151 | 3/20 | 0.59 |
| ▸ | NT5E | P21589 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086934 | 0.79 | GPBAR1 (0.80) | GPBAR1GLI1NT5EPTPN1LMNA | |
| SCHEMBL4363308 | 0.75 | GPBAR1 (0.73) | GPBAR1GLI1NT5EPTPN1LMNA | |
| SCHEMBL30138183 | 0.75 | GPBAR1 (0.73) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL14112012 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL22251646 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL23132693 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL13285621 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL21264235 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL7746410 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA | |
| Betulinic Acid SCHEMBL15362678 | 0.75 | RORC (1.00) | GPBAR1GLI1NT5EPTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103702675-B | Rhus verniciflua Stokes extract with increased content of active flavonoid compounds and its preparation method | AZI有限公司 | 2017-06-23 | — | — | CN | disclosed |
| EP-2604274-B1 | RHUS VERNICIFLUA STOKES EXTRACT HAVING INCREASED CONTENT OF ACTIVE FLAVONOID COMPOUND AND METHOD FOR PREPARING SAME | AZI COMPANY LTD (KR) | 2016-07-13 | — | — | EP | disclosed |
| US-20150110862-A1 | Sweet Gum Fruit Extract as a Therapeutic Agent | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2015-04-23 | — | — | US | disclosed |
| US-8859014-B2 | Method of converting fustin to fisetin | AZI COMPANY LTD. (KR) | 2014-10-14 | — | — | US | disclosed |
| CN-103702675-A | Rhus verniciflua Stokes extract with increased content of active flavonoid compounds and its preparation method | AZI COMPANY LTD | 2014-04-02 | — | — | CN | disclosed |
| US-20140031567-A1 | Method of Converting Fustin to Fisetin | AZI COMPANY LTD. (KR) | 2014-01-30 | — | — | US | disclosed |
| US-8551537-B2 | Rhus verniciflua stokes extract having increased content of active flavonoid compound and method for preparing same | AZI COMPANY LTD. (KR) | 2013-10-08 | — | — | US | disclosed |
| EP-2604274-A1 | RHUS VERNICIFLUA STOKES EXTRACT HAVING INCREASED CONTENT OF ACTIVE FLAVONOID COMPOUND AND METHOD FOR PREPARING SAME | Azi. Co., Ltd (KR) | 2013-06-19 | — | — | EP | disclosed |
| US-20120283322-A1 | Rhus Verniciflua Stokes Extract Having Increased Content Of Active Flavonoid Compound And Method For Preparing Same | AZI COMPANY LTD. (KR) | 2012-11-08 | — | — | US | disclosed |
| US-20100189830-A1 | Sweet Gum Fruit Extract as a Therapeutic Agent | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-07-29 | — | — | US | disclosed |
| WO-2008144706-A2 | SWEET GUM FRUIT EXTRACT AS A THERAPEUTIC AGENT | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283322-A1 | Rhus Verniciflua Stokes Extract Having Increased Content Of Active Flavonoid Compound And Method For Preparing Same | FUS, FLOT1, FIS1 | GPBAR1 4449/4885GLI1 872/4885NT5E 3207/4885 |
| US-20140031567-A1 | Method of Converting Fustin to Fisetin | FUS, RFTN1, HRAS | GPBAR1 4165/4885GLI1 980/4885NT5E 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.