Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711181 | 0.97 | CA1 (0.44) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL10749628 | 0.87 | PTGES2 (0.46) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL8868136 | 0.86 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL28867499 | 0.86 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL29469878 | 0.81 | CA1 (0.50) | ALDH1A1LMNANPC1RAB9AKMT2A | |
| SCHEMBL13589549 | 0.81 | CASR (0.42) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL1649916 | 0.81 | CA1 (0.50) | ALDH1A1LMNANPC1RAB9AKMT2A | |
| SCHEMBL10756934 | 0.81 | PTGES2 (0.40) | ALDH1A1SMN1; SMN2LMNAKDM4EL3MBTL1 | |
| SCHEMBL5349206 | 0.80 | L3MBTL1 (0.61) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL4101620 | 0.80 | L3MBTL1 (0.61) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |