SCHEMBL4101620

SCHEMBL4101620

COCCOCCOCCOc1ccccc1OCCOCCOCCOC

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 7/20 0.61
ALDH1A1 P00352 5/20 0.53
LMNA P02545 4/20 0.53
KDM4E B2RXH2 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
POLB P06746 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
MAPT P10636 5/20 0.51
TDP1 Q9NUW8 1/20 0.51
JAK2 O60674 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
PTK2B Q14289 1/20 0.50
ADRB2 P07550 3/20 0.47
ADRB1 P08588 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
AR P10275 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5349206 1.00 L3MBTL1 (0.61) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL5316970 0.94 L3MBTL1 (0.71) L3MBTL1ALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL2974587 0.93 MAPT (0.56) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL8867967 0.92 L3MBTL1 (0.63) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL27082331 0.92 L3MBTL1 (0.63) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL21169162 0.88 ALDH1A1 (0.50) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL8447030 0.87 L3MBTL1 (0.50) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL5318074 0.86 L3MBTL1 (0.61) L3MBTL1ALDH1A1LMNASMN1; SMN2POLB
SCHEMBL8977149 0.86 L3MBTL1 (0.79) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL10584222 0.86 CYP1A2 (0.59) L3MBTL1ALDH1A1LMNAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323204-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-18 US disclosed
US-10323204-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-18 US disclosed
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-08-03 US disclosed
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-08-03 US disclosed
WO-2016025467-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-18 WO disclosed
WO-2015060985-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-04-30 WO disclosed
US-20150119307-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-04-30 US disclosed
US-20150119307-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-04-30 US disclosed
US-20150119307-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-04-30 US disclosed
US-20090105633-A1 ULTRASOUND ASSEMBLY FOR USE WITH LIGHT ACTIVATED DRUGS TACHIBANA KATSURO 2009-04-23 US disclosed
US-20030092667-A1 Delivery of therapeutic compositions using ultrasound EKOS L.L.C. 2003-05-15 US disclosed
EP-0724457-B1 RADIATION SENSITIZATION USING TEXAPHYRINS UNIV TEXAS (US) 2003-03-05 EP disclosed
US-6527759-B1 Ultrasound assembly for use with light activated drugs EKOS CORPORATION 2003-03-04 US disclosed
US-6176842-B1 Ultrasound assembly for use with light activated drugs EKOS CORPORATION 2001-01-23 US disclosed
US-6069140-A RADIATION SENSITIZERS THE BOARD OF REGENTS UNIVERSITY OF TEXAS SYSTEM (US) 2000-05-30 US disclosed
US-5969111-A RADIATION SENSISTIZERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1999-10-19 US disclosed
WO-1999013943-A1 ULTRASOUND ASSEMBLY FOR USE WITH LIGHT ACTIVATED DRUGS EKOS CORPORATION (US) 1999-03-25 WO disclosed
US-5580543-A TEXAPHYRINS AS RADIATION SENSITIZERS PHARMACYCLICS, INC. (US) 1996-12-03 US disclosed
EP-0724457-A1 RADIATION SENSITIZATION USING TEXAPHYRINS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1996-08-07 EP disclosed
WO-1995010307-A1 RADIATION SENSITIZATION USING TEXAPHYRINS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10323204-B2 Low viscosity, low volatility lubricating oil basestocks TYK2, JAK1, CEL L3MBTL1 2858/4885ALDH1A1 2264/4885LMNA 2748/4885
US-20030092667-A1 Delivery of therapeutic compositions using ultrasound SON, XRCC6, DNASE1 L3MBTL1 850/4885ALDH1A1 4703/4885LMNA 78/4885
US-20150119307-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS TYK2, JAK1, CEL L3MBTL1 2858/4885ALDH1A1 2264/4885LMNA 2748/4885
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES SQOR, NDUFS4, NDUFS3 L3MBTL1 3199/4885ALDH1A1 1024/4885LMNA 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.