Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931968 | 0.97 | ALDH1A1 (0.45) | CA1CA2CA9CA5APTGES2 | |
| SCHEMBL29469878 | 0.84 | CA1 (0.50) | CA1CA2CA9CA5APTGES2 | |
| SCHEMBL1649916 | 0.84 | CA1 (0.50) | CA1CA2CA9CA5APTGES2 | |
| SCHEMBL13589549 | 0.84 | CASR (0.42) | ALDH1A1LMNASMN1; SMN2JAK2GAA | |
| SCHEMBL10749628 | 0.83 | PTGES2 (0.46) | CA1CA2CA9PTGES2CA4 | |
| SCHEMBL10756934 | 0.83 | PTGES2 (0.40) | CA1CA2CA9CA5APTGES2 | |
| SCHEMBL1334805 | 0.83 | CYP2C9 (0.56) | CA1CA2CA9CA5APTGES2 | |
| SCHEMBL28867499 | 0.82 | L3MBTL1 (0.46) | CYP2C9ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL8868136 | 0.82 | L3MBTL1 (0.46) | CYP2C9ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3373463 | 0.81 | MEN1 (0.53) | CA1CA2CA9CA5APTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| US-4510325-A | Phenyl sulfonamides | CIBA-GEIGY CORPORATION (US) | 1985-04-09 | — | — | US | claimed |
| CN-114920616-B | Synthesis process of amidine compound | 南京师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-114920616-A | Synthetic process of amidine compound | 南京师范大学 | 2022-08-19 | — | — | CN | disclosed |
| EP-0237480-B1 | PROCESS FOR THE PREPARATION OF 2-ALKOXYBENZENESULPHON AMIDES | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |
| EP-0359160-A2 | Process for the preparation of 2-alkoxy-benzosulfonamide compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-21 | — | — | EP | disclosed |
| US-4798688-A | 2-alkoxy-5-chloro-benzenesulfonates useful for the preparation of 2-alkoxybenzosulfonamides | CIBA-GEIGY CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4709092-A | Process for the preparation of 2-alkoxybenzosulfonamides | CIBA-GEIGY CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0237480-A2 | Process for the preparation of 2-alkoxybenzenesulphon amides | CIBA-GEIGY AG (CH) | 1987-09-16 | — | — | EP | disclosed |
| US-4479821-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4419121-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1983-12-06 | — | — | US | disclosed |