Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867499 | 1.00 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL29931968 | 0.86 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8868141 | 0.83 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL9711181 | 0.82 | CA1 (0.44) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL13589549 | 0.80 | CASR (0.42) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL7356282 | 0.80 | NPC1 (0.43) | L3MBTL1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL5349206 | 0.79 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4101620 | 0.79 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL995712 | 0.79 | CYP1A2 (0.51) | L3MBTL1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL3371631 | 0.78 | CYP3A4 (0.49) | L3MBTL1LMNANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686486-A | 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl b!pyran-2-ones useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |