Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932060 | 0.72 | ALDH1A1 (0.39) | DRD4GRM2TRPV1SLC6A2SLC6A3 | |
| SCHEMBL23536396 | 0.72 | ALDH1A1 (0.39) | DRD4GRM2TRPV1SLC6A2SLC6A3 | |
| SCHEMBL29931935 | 0.68 | ALDH1A1 (0.44) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL23536527 | 0.68 | ALDH1A1 (0.44) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL18434217 | 0.68 | L3MBTL1 (0.54) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL17543687 | 0.68 | ALDH1A1 (0.59) | DRD4GRM2KMT2AALDH1A1LMNA | |
| SCHEMBL29931936 | 0.68 | ALDH1A1 (0.59) | DRD4GRM2KMT2AALDH1A1LMNA | |
| SCHEMBL24628365 | 0.66 | ALDH1A1 (0.58) | DRD4GRM2KMT2AMAPTALDH1A1 | |
| SCHEMBL23536400 | 0.66 | P2RX7 (0.38) | DRD4GRM2TRPV1SLC6A2SLC6A3 | |
| SCHEMBL29932228 | 0.65 | ALDH1A1 (0.61) | KMT2AMAPTMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |