Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.84 |
| ▸ | DRD3 | P35462 | 6/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.63 |
| ▸ | HTR3B | O95264 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23411580 | 1.00 | DRD2 (0.84) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| Hydrochloric Acid SCHEMBL23411057 | 0.99 | DRD2 (0.82) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| Hydrochloric Acid SCHEMBL23411056 | 0.97 | DRD2 (0.80) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| SCHEMBL23439606 | 0.80 | DRD2 (0.59) | DRD2DRD3CYP2C19LMNAUSP2 | |
| SCHEMBL6366499 | 0.78 | HTR3A (1.00) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| SCHEMBL379 | 0.78 | HTR3A (1.00) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| SCHEMBL29396943 | 0.78 | HTR3A (1.00) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| SCHEMBL17376349 | 0.77 | DRD2 (0.58) | DRD2DRD3CYP2C19HTR3AHTR3E | |
| SCHEMBL23411220 | 0.77 | DRD2 (0.51) | DRD2CYP2C19CYP2D6USP2SLC6A2 | |
| Hydrochloric Acid SCHEMBL246416 | 0.77 | LMNA (1.00) | DRD2DRD3CYP2C19HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210238-B | Substituted aminoquinolones as dgkα inhibitors for immune activation | 拜耳公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115210238-A | Substituted aminoquinolones as DGK alpha inhibitors for immune activation | 拜耳公司 | 2022-10-18 | — | — | CN | disclosed |