Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38659451 | 0.80 | HSD11B1 (0.51) | RIPK1ALDH1A1MAPK1HSD11B1NUDT1 | |
| SCHEMBL8296762 | 0.80 | HSD11B1 (0.51) | RIPK1ALDH1A1MAPK1HSD11B1NUDT1 | |
| SCHEMBL29679482 | 0.80 | GPR119 (0.46) | PIK3C3RIPK1ALDH1A1HSD11B1PRMT5 | |
| SCHEMBL12944620 | 0.80 | BACE1 (0.51) | PIK3C3RIPK1MAPK1HTTUSP19 | |
| SCHEMBL31430923 | 0.79 | PRMT5 (0.55) | RIPK1ALDH1A1MAPK1HSD11B1NUDT1 | |
| SCHEMBL29504572 | 0.79 | PRMT5 (0.55) | RIPK1ALDH1A1MAPK1HSD11B1NUDT1 | |
| SCHEMBL31364807 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPK1CPT1AHTT | |
| SCHEMBL30499343 | 0.77 | RIPK1 (0.42) | RIPK1ALDH1A1KDM4EHSD17B10HHAT | |
| SCHEMBL30398913 | 0.77 | CDK5 (0.40) | RIPK1ALDH1A1HSD11B1HHATCASP1 | |
| SCHEMBL5321655 | 0.77 | RIPK1 (0.40) | RIPK1KDM4EHSD17B10HHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |