SCHEMBL29934249

SCHEMBL29934249

CC(=NO)C(C)=NNC(N)=S

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 2/20 0.42
CTSK P43235 1/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
ALOX12 P18054 1/20 0.40
NR2F2 P24468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1641313 0.76 ALDH1A1 (0.47) METTL3CTSKATMALDH1A1
SCHEMBL10812143 0.74 ATM (0.63) METTL3CTSKATMALDH1A1
SCHEMBL2024987 0.74 ALDH1A1 (0.46) METTL3CTSKATMALDH1A1
SCHEMBL2024988 0.74 ALDH1A1 (0.46) METTL3CTSKATMALDH1A1
SCHEMBL233447 0.74
SCHEMBL10812209 0.73 CTSL (0.55) METTL3ATM
SCHEMBL18185230 0.73 METTL3 (0.48) METTL3CTSKATM
SCHEMBL18185231 0.73 METTL3 (0.48) METTL3CTSKATM
SCHEMBL9129184 0.73 METTL3 (0.40) METTL3CTSKATMALDH1A1SMN1; SMN2
SCHEMBL9129195 0.73 METTL3 (0.40) METTL3CTSKATMALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 US disclosed