Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592549 | 1.00 | XPO1 (0.56) | XPO1ALDH1A1MAPTGAAENPP3 | |
| SCHEMBL1592361 | 0.88 | XPO1 (0.67) | XPO1MAPTL3MBTL1SMN1; SMN2CRHR1 | |
| SCHEMBL1592533 | 0.87 | XPO1 (0.59) | XPO1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1592551 | 0.84 | XPO1 (0.38) | XPO1ALDH1A1MAPTGAAENPP3 | |
| SCHEMBL1592387 | 0.81 | XPO1 (0.53) | XPO1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1592940 | 0.77 | XPO1 (0.46) | XPO1MAPT | |
| SCHEMBL1592575 | 0.73 | LMNA (0.51) | XPO1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1592535 | 0.72 | XPO1 (0.41) | XPO1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1592523 | 0.72 | XPO1 (1.00) | XPO1PARP1 | |
| SCHEMBL23872048 | 0.72 | XPO1 (0.52) | XPO1ALDH1A1MAPTGAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074704-A1 | QUINOLINE COMPOUNDS WITH ANTI-CANCER ACTIVITY | CanBas Co., Ltd. (JP) | 2022-10-19 | — | — | EP | disclosed |