SCHEMBL29517025

SCHEMBL29517025

C=C(C)C(O)Cc1c(O)c(C(=O)C(C)CC)c(O)c2c(CCC)cc(=O)oc12

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 17/20 0.70
▸ EPAS1 Q99814 17/20 0.70
▸ MEN1 O00255 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ FBP1 P09467 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934508 0.77 HIF1A (1.00) HIF1AEPAS1
SCHEMBL29517160 0.75 HIF1A (0.60) HIF1AEPAS1MEN1LMNAKMT2A
Achyrofuran SCHEMBL505137 0.74 HIF1A (0.57) HIF1AEPAS1MEN1LMNATP53
Achyrofuran SCHEMBL29375603 0.74 HIF1A (0.57) HIF1AEPAS1MEN1LMNATP53
SCHEMBL29517117 0.67 HIF1A (0.70) HIF1AEPAS1MEN1LMNATP53
SCHEMBL29520661 0.67 HIF1A (1.00) HIF1AEPAS1
SCHEMBL7028753 0.65 HIF1A (0.52) HIF1AEPAS1MEN1MAPTMAPK1
SCHEMBL30927109 0.64 HIF1A (0.71) HIF1AEPAS1MEN1LMNAKMT2A
SCHEMBL5914907 0.62 ALDH1A1 (0.53) HIF1AEPAS1MEN1MAPTMAPK1
SCHEMBL15501063 0.62 HIF1A (0.51) HIF1AEPAS1MEN1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250311723-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS IMPELLO BIOSCIENCES, INC. 2025-10-09 — — US disclosed
US-20230200385-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS IMPELLO BIOSCIENCES, INC. 2023-06-29 — — US disclosed
EP-4188090-A2 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS Impello Biosciences, Inc. (US) 2023-06-07 — — EP disclosed
US-11638427-B2 Methods and compositions for altering secondary metabolites in plants IMPELLO BIOSCIENCES, INC. (US) 2023-05-02 — — US disclosed
US-20220079150-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS IMPELLO BIOSCIENCES, INC. 2022-03-17 — — US disclosed
WO-2022026613-A2 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS IMPELLO BIOSCIENCES, INC. (US) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220079150-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS ERG28, AHCY, BROX HIF1A 3054/4885EPAS1 2165/4885MEN1 2970/4885
US-20250311723-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS ERG28, AHCY, BROX HIF1A 3054/4885EPAS1 2165/4885MEN1 2970/4885
US-11638427-B2 Methods and compositions for altering secondary metabolites in plants ERG28, AHCY, BROX HIF1A 3054/4885EPAS1 2165/4885MEN1 2970/4885
US-20230200385-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS ERG28, AHCY, BROX HIF1A 3054/4885EPAS1 2165/4885MEN1 2970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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