Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250594 | 1.00 | PKM (0.41) | PKMNLRP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14987851 | 1.00 | PKM (0.41) | PKMNLRP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14987814 | 1.00 | PKM (0.41) | PKMNLRP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13940824 | 0.85 | PKM (0.31) | PKMNLRP3CYP3A4LMNATP53 | |
| SCHEMBL530805 | 0.75 | NLRP3 (0.36) | PKMNLRP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4022686 | 0.73 | GAA (0.32) | TSHR | |
| Alloalantolactone SCHEMBL30105635 | 0.73 | NLRP3 (0.50) | PKMNLRP3CYP3A4CYP2D6CYP2C9 | |
| Alloalantolactone SCHEMBL29934802 | 0.73 | NLRP3 (0.50) | PKMNLRP3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL529984 | 0.72 | CYP3A4 (0.52) | CYP3A4TDP1CYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL14973480 | 0.72 | CYP3A4 (0.52) | CYP3A4TDP1CYP19A1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136809-A1 | 7-HYRDROXYFRULLANOLIDE ITS ANALOGS FOR PREVENTION CONTROL AND TREATMENT OF METABOLIC DISORDERS | LAILA NUTRACEUTICALS (IN) | 2013-05-30 | — | — | US | disclosed |
| US-20130136809-A1 | 7-HYRDROXYFRULLANOLIDE ITS ANALOGS FOR PREVENTION CONTROL AND TREATMENT OF METABOLIC DISORDERS | LAILA NUTRACEUTICALS (IN) | 2013-05-30 | — | — | US | disclosed |
| WO-2012014216-A1 | 7-HYDROXYFRULLANOLIDE AND ITS ANALOGS FOR PREVENTION, CONTROL AND TREATMENT OF METABOLIC DISORDERS | LAILA NUTRACEUTICALS (IN) | 2012-02-02 | — | — | WO | disclosed |
| WO-2009016565-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136809-A1 | 7-HYRDROXYFRULLANOLIDE ITS ANALOGS FOR PREVENTION CONTROL AND TREATMENT OF METABOLIC DISORDERS | GPR119, NPY2R, NPY5R | PKM 3077/4885NLRP3 1438/4885CYP3A4 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.