Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936878 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBSMN1; SMN2HPGD | |
| SCHEMBL25332785 | 0.82 | SLC6A3 (0.50) | ALDH1A1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL28835940 | 0.80 | SLC6A2 (0.47) | KIF11ALDH1A1KMT2APOLBMAPK1 | |
| SCHEMBL505248 | 0.79 | LMNA (0.57) | ALDH1A1KMT2AMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL505395 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL505633 | 0.77 | TSHR (0.46) | ALDH1A1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL29936785 | 0.77 | L3MBTL1 (0.49) | ALDH1A1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL29106646 | 0.76 | LMNA (0.58) | ALDH1A1KMT2APOLBSMN1; SMN2MEN1 | |
| SCHEMBL29936482 | 0.76 | RARB (0.50) | NPC1TP53TSHR | |
| SCHEMBL14930553 | 0.76 | CA1 (0.58) | EPHX2KIF11MRGPRX4ADORA3AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010600-B | Method for synthesizing polyfluoroaryl carboxylic acid compound based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115010600-A | Method for synthesizing polyfluoroaryl carboxylic acid compounds based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |