Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.56 |
| ▸ | ATP4A | P20648 | 1/20 | 0.44 |
| ▸ | ATP4B | P51164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167786 | 1.00 | LTA4H (0.56) | LTA4HKCNH2ATP4AATP4B | |
| SCHEMBL4693436 | 0.91 | LTA4H (0.51) | LTA4HKCNH2ATP4AATP4B | |
| SCHEMBL2168385 | 0.90 | LTA4H (0.58) | LTA4HKCNH2 | |
| SCHEMBL2167904 | 0.88 | LTA4H (0.56) | LTA4HKCNH2 | |
| SCHEMBL4693779 | 0.88 | LTA4H (0.54) | LTA4HKCNH2 | |
| SCHEMBL2168410 | 0.88 | LTA4H (0.52) | LTA4HKCNH2 | |
| SCHEMBL2169597 | 0.86 | LTA4H (0.55) | LTA4HKCNH2 | |
| SCHEMBL4693776 | 0.86 | LTA4H (0.52) | LTA4HKCNH2 | |
| SCHEMBL2169020 | 0.85 | LTA4H (0.54) | LTA4HKCNH2 | |
| SCHEMBL4693774 | 0.85 | LTA4H (0.59) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220226304-A1 | Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase | ALKAHEST, INC. | 2022-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220226304-A1 | Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase | LTA4H, LTB4R, LTC4S | LTA4H 1/4885KCNH2 3977/4885ATP4A 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.