Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | GPR142 | Q7Z601 | 5/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989514 | 0.80 | GAA (0.50) | GPR142KDM4C | |
| SCHEMBL5015520 | 0.77 | KCNH3 (0.62) | — | |
| SCHEMBL7992030 | 0.76 | GPR142 (0.49) | MAOAGPR142KDM4CSLC6A3 | |
| SCHEMBL6031397 | 0.73 | GAA (0.53) | GPR142 | |
| SCHEMBL30373802 | 0.71 | MAOA (1.00) | MAOAMAOB | |
| SCHEMBL522503 | 0.71 | MAOA (1.00) | MAOAMAOB | |
| SCHEMBL11207065 | 0.70 | MAOA (0.50) | MAOAMAOBTAAR1LTA4H | |
| SCHEMBL523447 | 0.70 | MAOA (0.64) | MAOAMAOBTAAR1LTA4H | |
| SCHEMBL2736262 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4509967 | 0.69 | MAOA (0.96) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226203-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION (US) | 2022-10-27 | — | — | WO | disclosed |