Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031397 | 0.85 | GAA (0.53) | GPR142BCHEHDAC1GAAMAPT | |
| SCHEMBL18157933 | 0.84 | KDM4C (0.42) | GPR142MEN1KMT2ATDP1SLC6A3 | |
| SCHEMBL15313384 | 0.82 | CYP1A2 (0.64) | TDP1KDM4CTP53CHRM2 | |
| SCHEMBL7533150 | 0.77 | LTA4H (0.48) | GPR142TDP1SLC6A3 | |
| SCHEMBL29937460 | 0.76 | MAOA (0.55) | GPR142SLC6A3KDM4CMAOA | |
| SCHEMBL13258500 | 0.75 | GPR142 (0.58) | GPR142 | |
| SCHEMBL5799878 | 0.73 | MEN1 (0.78) | MEN1KMT2ATDP1BCHEMAOA | |
| SCHEMBL1654 | 0.73 | MEN1 (0.78) | MEN1KMT2ATDP1BCHEMAOA | |
| Benzene SCHEMBL11697595 | 0.73 | MEN1 (0.78) | MEN1KMT2ATDP1BCHEMAOA | |
| SCHEMBL2947235 | 0.72 | ALDH1A1 (0.63) | MEN1KMT2ATDP1KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277871-B1 | ANTICANCER AGENTS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |