Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29938322 | 0.89 | ADRA1D (0.60) | GAACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29937951 | 0.85 | HRH3 (0.61) | GAACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29937768 | 0.80 | PSMB1 (0.60) | GAACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21296813 | 0.79 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BCACNA1BKDM4E | |
| SCHEMBL5640119 | 0.79 | HRH3 (0.69) | MAPTPOLBKDM4EALDH1A1HRH3 | |
| SCHEMBL21296764 | 0.77 | HRH3 (0.58) | ADRA1DADRA1AADRA1BMAPTCACNA1B | |
| SCHEMBL14287848 | 0.77 | HRH3 (0.66) | CYP1A2CYP2D6CYP2C9MAPTPOLB | |
| SCHEMBL5106634 | 0.77 | GLA (0.73) | CYP1A2CYP2D6CYP2C9MAPTNPSR1 | |
| SCHEMBL11937419 | 0.76 | KDM4E (0.95) | KDM4EALDH1A1NPC1HRH3 | |
| SCHEMBL21296734 | 0.76 | PSMB1 (0.51) | GAACYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | University of Florida Research Fooundation, Incorporated (US) | 2024-07-25 | — | — | US | disclosed |
| WO-2022226133-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | IL6, IL6ST, IL36G | GAA 545/4885CYP1A2 3681/4885CYP2D6 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.