SCHEMBL2993885

SCHEMBL2993885

NC(=O)NCCCC(N)(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7718396 0.79 ALOX15 (0.41) ALDH1A1POLBSMN1; SMN2
SCHEMBL18676095 0.78 TSHR (0.33) TSHR
SCHEMBL20978268 0.78 ARG1 (0.50) TSHRALDH1A1POLB
SCHEMBL1504428 0.78 ARG1 (0.50) TSHRALDH1A1POLB
SCHEMBL1455221 0.78 ARG1 (0.50) TSHRALDH1A1POLB
SCHEMBL30153590 0.78 ARG1 (0.40) ALDH1A1SMN1; SMN2
SCHEMBL24395222 0.76 ACLY (0.46) TSHRSMN1; SMN2
SCHEMBL4670028 0.76 KDM4E (0.33)
SCHEMBL8210559 0.76 PAOX (0.32) TSHR
SCHEMBL9191890 0.76 ARG1 (0.53) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 US disclosed
US-7776844-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2010-08-17 US disclosed
US-20090208499-A1 N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use YU RUEY J 2009-08-20 US disclosed
US-7572776-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2009-08-11 US disclosed
US-20080306025-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2008-12-11 US disclosed
US-7429575-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2008-09-30 US disclosed
US-20070161543-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2007-07-12 US disclosed
WO-2005102043-A2 USE OF NICKEL TO CORRECT GROWTH DISORDERS IN PLANTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-11-03 WO disclosed
US-20050245397-A1 Use of nickel to correct growth disorders in plants NIPAN, LLC 2005-11-03 US disclosed