SCHEMBL29939570

SCHEMBL29939570

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.56
▸ OPRD1 P41143 4/20 0.56
▸ LTA4H P09960 1/20 0.56
▸ MME P08473 2/20 0.55
▸ BACE1 P56817 4/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ BACE2 Q9Y5Z0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27983689 0.92 LTA4H (0.64) OPRM1OPRD1LTA4HMMEOPRK1
SCHEMBL30903467 0.90 LTA4H (0.65) OPRM1OPRD1LTA4HMME
SCHEMBL30122976 0.89 OPRM1 (0.56) OPRM1OPRD1BACE1OPRK1BACE2
SCHEMBL30799804 0.88 OPRM1 (0.60) OPRM1OPRD1LTA4HMMEBACE1
SCHEMBL31215110 0.88 OPRM1 (0.56) OPRM1OPRD1MMEBACE1OPRK1
SCHEMBL29775590 0.88 BACE1 (0.55) OPRM1OPRD1LTA4HMMEBACE1
SCHEMBL29947099 0.88 LTA4H (0.55) OPRM1OPRD1LTA4HMMEBACE1
SCHEMBL8975237 0.88 LTA4H (0.60) LTA4HMME
SCHEMBL30903454 0.87 OPRK1 (0.55) OPRM1OPRD1LTA4HMMEBACE1
SCHEMBL30799912 0.87 BACE1 (0.64) OPRM1OPRD1BACE1OPRK1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243509-A1 METHODS FOR TREATING EYE DISEASE MUSC FOUND FOR RES DEV (US) 2025-07-31 — — US disclosed
US-11945848-B2 Chimeric inhibitor molecules of complement activation OMEROS CORPORATION (US) 2024-04-02 — — US disclosed
US-20230295252-A1 CHIMERIC INHIBITOR MOLECULES OF COMPLEMENT ACTIVATION OMEROS CORPORATION (US) 2023-09-21 — — US disclosed
US-20230103708-A1 METHODS FOR TREATING EYE DISEASE MUSC FOUND FOR RES DEV (US) 2023-04-06 — — US disclosed
US-11453709-B2 Chimeric inhibitor molecules of complement activation OMEROS CORPORATION (US) 2022-09-27 — — US disclosed
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