SCHEMBL30122976

SCHEMBL30122976

CC(C)C[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 3/20 0.56
▸ OPRD1 P41143 3/20 0.56
▸ BACE1 P56817 5/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ BACE2 Q9Y5Z0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29947099 0.94 LTA4H (0.55) OPRM1OPRD1BACE1BACE2
SCHEMBL30785946 0.94 OPRM1 (0.65) OPRM1OPRD1BACE1OPRK1BACE2
SCHEMBL31482433 0.92 LTA4H (0.57) —
SCHEMBL31602914 0.92 LTA4H (0.57) —
SCHEMBL31357930 0.90 OPRM1 (0.56) OPRM1OPRD1BACE1OPRK1
SCHEMBL29939570 0.89 OPRM1 (0.56) OPRM1OPRD1BACE1OPRK1BACE2
SCHEMBL31215110 0.88 OPRM1 (0.56) OPRM1OPRD1BACE1OPRK1
SCHEMBL30504227 0.88 OPRM1 (0.62) OPRM1OPRD1BACE1
SCHEMBL29601744 0.87 BACE1 (0.60) BACE1BACE2
SCHEMBL30904490 0.87 OPRM1 (0.61) OPRM1OPRD1BACE1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
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