Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MC4R | P32245 | 13/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24641660 | 0.85 | MEN1 (0.59) | KMT2AMEN1GAAMC4R | |
| SCHEMBL30017789 | 0.85 | MEN1 (0.59) | KMT2AMEN1GAAMC4R | |
| SCHEMBL29939233 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL27093513 | 0.80 | GAA (0.55) | KMT2AMEN1GAAMC4RMPO | |
| SCHEMBL418681 | 0.80 | RBP4 (0.46) | KMT2AMEN1GAAMC4R | |
| SCHEMBL29939353 | 0.79 | KMT2A (0.50) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL29939675 | 0.79 | MAPT (0.50) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL27737040 | 0.76 | GRM5 (0.48) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL1902630 | 0.75 | NCF1 (0.55) | KMT2AMEN1GAAMC4RLMNA | |
| SCHEMBL2558196 | 0.73 | KMT2A (0.59) | KMT2AMEN1GAAMC4RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218440-A1 | FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 青岛睿吉医疗技术有限公司 | 2022-10-20 | — | — | WO | disclosed |