Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29939233 | 0.87 | ALDH1A1 (0.53) | MAPTMEN1KMT2AGAAHTT | |
| SCHEMBL24641798 | 0.84 | GPR119 (0.50) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL30017169 | 0.84 | GPR119 (0.50) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL29939879 | 0.79 | KMT2A (0.60) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL18586080 | 0.78 | GRM5 (0.52) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL14830657 | 0.78 | ITGB3 (0.48) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL27857403 | 0.77 | HTR1A (0.50) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL29939249 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL5238969 | 0.75 | USP2 (0.59) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL14830659 | 0.75 | SIGMAR1 (0.50) | MAPTMEN1KMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218440-A1 | FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 青岛睿吉医疗技术有限公司 | 2022-10-20 | — | — | WO | disclosed |