SCHEMBL29940375

SCHEMBL29940375

CC1(CNC(=O)[C@H](CN)NC(=O)c2ccc(C#Cc3ccccc3)cc2)NC(=O)NC1=O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADAM17 P78536 1/20 0.44
ADAMTS4 O75173 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39
ADAMTS5 Q9UNA0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023704 0.90 CTSB (0.45) ADAM17ADAMTS4MMP2MMP3MMP12
SCHEMBL29625501 0.85 ADAM17 (0.46) ADAM17
SCHEMBL12378634 0.84 ADAM17 (0.56) ADAM17ADAMTS4MMP2MMP3MMP12
SCHEMBL29494606 0.82 ADAMTS5 (0.39) ADAM17ADAMTS4MMP2MMP3MMP12
SCHEMBL14196095 0.77
SCHEMBL31664382 0.75 ADAM17 (0.46) ADAM17ADAMTS4MMP2MMP3MMP12
SCHEMBL398571 0.75
SCHEMBL12416690 0.74 ADAM17 (0.57) ADAM17ADAMTS4MMP2MMP3MMP12
SCHEMBL2874514 0.74 PIN1 (0.54)
SCHEMBL25728515 0.73 PIN1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573535-B1 METHOD FOR PLACING AN EMERGENCY CALL AUDI AG (DE) 2026-03-11 EP disclosed
EP-4573535-A1 METHOD FOR PLACING AN EMERGENCY CALL AUDI AG (DE) 2025-06-25 EP disclosed
CN-119731716-A Method for making an emergency call 奥迪股份公司 2025-03-28 CN disclosed
US-20240350655-A1 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS FORSCHUNGSVERBUND BERLIN E.V. (DE) 2024-10-24 US disclosed
CN-115243719-B CTB006 and Ponatinib combined application 北京先通生物医药技术有限公司 2024-09-13 CN disclosed
EP-4326335-A1 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS Forschungsverbund Berlin E.V. (DE) 2024-02-28 EP disclosed
WO-2024037864-A1 METHOD FOR PLACING AN EMERGENCY CALL AUDI AG (DE) 2024-02-22 WO disclosed
CN-117545511-A Thiol coupling with unsaturated phosphorus (V) compounds 柏林合作研究学会 2024-02-09 CN disclosed
US-20230112450-A1 COMBINED USE OF CTB006 AND PONATINIB BEIJING SINOTAU BIO-PHARMACEUTICALS TECHNOLOGY CO., LTD. (CN) 2023-04-13 US disclosed
WO-2022223783-A9 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS FORSCHUNGSVERBUND BERLIN E.V. (DE) 2023-03-02 WO disclosed
EP-4115902-A1 COMBINED USE OF CTB006 AND PONATINIB Beijing Sinotau Bio-Pharmaceuticals Technology Co., Ltd. (CN) 2023-01-11 EP disclosed
WO-2022223783-A1 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS FORSCHUNGSVERBUND BERLIN E.V. (DE) 2022-10-27 WO disclosed
CN-115243719-A CTB006 and Ponatinib combined application 北京先通生物医药技术有限公司 2022-10-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240350655-A1 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS PTMS, PHOSPHO1, TYMP ADAM17 3617/4885ADAMTS4 2209/4885MMP2 3529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.