Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143252 | 1.00 | KDM4E (0.50) | KDM4ECYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL8513832 | 0.90 | MTNR1A (0.55) | BACE1MTNR1AHTR2CHTR2BMTNR1B | |
| SCHEMBL9476254 | 0.87 | KDM4E (0.50) | KDM4ECYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL15653946 | 0.85 | KMT2A (0.45) | KDM4EMAPTMAPK1KMT2AGAA | |
| SCHEMBL27524529 | 0.84 | MTNR1A (0.54) | KMT2AMTNR1AMTNR1B | |
| SCHEMBL27343133 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL27965594 | 0.83 | CYP3A4 (0.50) | KDM4ECYP3A4MAPTMAPK1KMT2A | |
| SCHEMBL10458103 | 0.83 | LMNA (0.54) | KDM4ECYP3A4LMNAGAAPOLB | |
| SCHEMBL8399022 | 0.83 | LMNA (0.50) | KDM4ELMNAMAPTMAPK1KMT2A | |
| SCHEMBL27504643 | 0.83 | CYP3A4 (0.54) | KDM4ECYP3A4LMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308615-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W. R. Grace & Co.-Conn (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197491-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W.R. GRACE & CO.-CONN. (US) | 2022-09-22 | — | — | WO | disclosed |