Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458013 | 0.87 | LMNA (0.54) | LMNACYP1A2CYP3A4ACHEKDM4E | |
| SCHEMBL10456637 | 0.86 | ELANE (0.46) | LMNACYP1A2CYP2A6KDM4EALDH1A1 | |
| SCHEMBL1143252 | 0.83 | KDM4E (0.50) | LMNACYP3A4ACHEKDM4EGLA | |
| SCHEMBL27504643 | 0.83 | CYP3A4 (0.54) | LMNACYP3A4ACHEKDM4EGLA | |
| SCHEMBL29940384 | 0.83 | KDM4E (0.50) | LMNACYP3A4ACHEKDM4EGLA | |
| SCHEMBL27497870 | 0.83 | MAPT (0.50) | LMNACYP3A4KDM4EGLAGAA | |
| SCHEMBL10456608 | 0.83 | ALDH1A1 (0.53) | CYP1A2CYP2A6ACHEKDM4EGLA | |
| SCHEMBL13888153 | 0.82 | MTNR1A (0.54) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL29257065 | 0.82 | CYP3A4 (0.49) | LMNACYP3A4ACHEKDM4EGLA | |
| SCHEMBL995752 | 0.80 | MAPT (0.51) | LMNACYP3A4KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935537-A | OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4801737-A | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0170273-B1 | PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0170273-A2 | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-02-05 | — | — | EP | disclosed |