Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14500654 | 0.83 | TSHR (0.46) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29940577 | 0.83 | PTPN1 (0.68) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1143040 | 0.83 | PTPN1 (0.68) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9957302 | 0.81 | MAPK1 (0.49) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6940134 | 0.78 | KEAP1 (0.41) | KDM4EALDH1A1HSD17B10HPGDACHE | |
| SCHEMBL27597873 | 0.75 | PTGS2 (0.57) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2059537 | 0.74 | KDM4E (0.71) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5212814 | 0.74 | MAPK1 (0.71) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9957174 | 0.74 | TUBB4A (0.46) | PTPN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27584645 | 0.74 | TRPA1 (0.43) | KDM4EALDH1A1HSD17B10HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | claimed |