Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358790 | 0.95 | PLK1 (0.43) | ACACBPLK1AKR1C3AKR1C2GAA | |
| SCHEMBL11839273 | 0.84 | ALDH1A1 (0.45) | HAO1MMP13MMP12MMP2MMP9 | |
| SCHEMBL11835319 | 0.81 | LMNA (0.50) | HAO1MMP13MMP12MMP2MMP9 | |
| SCHEMBL7571366 | 0.81 | KMT2A (0.53) | ACACBGAAKMT2APTGS2 | |
| SCHEMBL7564000 | 0.81 | KMT2A (0.53) | ACACBGAAKMT2APTGS2 | |
| SCHEMBL7567588 | 0.81 | KMT2A (0.53) | ACACBGAAKMT2APTGS2 | |
| SCHEMBL29940797 | 0.81 | L3MBTL1 (0.43) | TDP1L3MBTL1KMT2A | |
| SCHEMBL28261002 | 0.79 | HPGD (0.49) | ACACBPLK1AKR1C3AKR1C2GAA | |
| SCHEMBL4038007 | 0.78 | ALDH1A1 (0.44) | MMP13MMP12ACACBPLK1MMP8 | |
| SCHEMBL11468387 | 0.76 | ACACB (0.42) | ACACBPLK1AKR1C3AKR1C2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108901-A | Synthetic method of alpha-hydroxycarboxylic acid compound | 四川大学 | 2022-09-27 | — | — | CN | disclosed |