Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25668139 | 1.00 | NR4A2 (0.46) | NR4A2PARP1LMNACYP1A2CYP2D6 | |
| SCHEMBL18283388 | 0.89 | NR4A2 (0.46) | NR4A2LMNACYP1A2CYP2D6MEN1 | |
| SCHEMBL437551 | 0.81 | NR4A2 (0.51) | NR4A2PARP1CYP1A2CYP2D6GABRA1 | |
| SCHEMBL1346739 | 0.81 | NR4A2 (0.43) | NR4A2PARP1LMNACYP1A2CYP2D6 | |
| SCHEMBL30120338 | 0.81 | ESR2 (0.42) | PARP1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL31384389 | 0.80 | MAOA (0.50) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6822558 | 0.80 | MAOA (0.50) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31413713 | 0.78 | NR4A2 (0.40) | NR4A2PARP1LMNAGABRA1GABRG2 | |
| SCHEMBL31384368 | 0.78 | LMNA (0.43) | LMNAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6786993 | 0.78 | PIK3CA (0.40) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557929-A | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-109715612-B | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |